The Immunogenicity of Human Hl-a Haplotypes as Measured by Skin Graft Survival times and Mixed Leukocyte Reactions
نویسندگان
چکیده
The immunogenicity of the haplotypes in 30 families was measured by survival of skin grafts between selected paired family members. These families were genotyped for HL-A using 57 selected cytotoxic alloantisera defining HL-A 1-12 as well as other nondefined specificities. Mixed leukocyte reactions were also studied in this series and the correlations between the mixed leukocyte reactions with skin graft survival times, individual HL-A specificities, and the number of incompatible HL-A alleles are reported. Comments concerning the interpretation and quantitation of the mixed leukocyte reactions are discussed.
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 133 شماره
صفحات -
تاریخ انتشار 1971